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Circularity Healthcare Joins Springer Publishing Company, Daily Nurse, and Minority Nurse In Recognizing Nurses and Giving Back

In these uncertain times, we must recognize and promote our nurses on the frontlines of the COVID-19 pandemic. Circularity Healthcare is finding ways to share in recognizing those who deserve recognition.

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“We’ve been on the lookout for publishers we can partner with who have the same goal as ours; that is, to help our front liners. In our participation with Springer Publishing’s Nurses’ Week 2020, we want to spread the message that D’OXYVA is readily available for them to keep them protected by boosting their immune system and by providing armor against infection,” said Jennifer Boadilla-Pelaez, Circularity Healthcare’s Senior Sales and Marketing Manager and Creative Director.

Last May, Springer Publishing Company launched its Nurses’ Week 2020 issue to help support and recognize nurses who are leading via change. In this special issue presented by Springer Publishing Company, Daily Nurse, and Minority Nurse, we’ll hear from frontline nurses, nurse researchers, and nurse educators to learn how they lead during the COVID-19 pandemic.

Circularity showed their support by securing a 2-page advertorial for this issue and showcased how to help front liners stay healthy during these uncertain times via its latest article discussing a new clinical trial involving Circularity’s already FDA-approved drug and IDE device D’OXYVA®, which could significantly increase the recovery rate for COVID-19 patients with underlying health conditions and save lives! Circularity has also been calling out all doctors and nurses that Circularity is accepting D’OXYVA donation requests.

(Read the full issue here: https://dailynurse.com/nurses-week-2020-special-issue/)

20% of all proceeds will be donated to the GLO GOOD Foundation, who have joined with the Society of Nurse Scientists Innovators Entrepreneurs and Leaders (SONSIEL) to launch an urgent call-to-action to move personal protective equipment (PPE) supplies, including vital respirator masks, to frontline health-care providers for COVID-19 patients.

About Springer Publishing

Springer Publishing is an award-winning publisher of health-care and behavioral sciences content, featuring books, apps, journals, and digital products. With an acute understanding of how educators teach, how practitioners work, and how students learn, we design our digital and print products for optimal outcomes for learners, patients, and clients. We’ve been proudly educating people in the health-care and helping professions for over 70 years.

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Circularity in collaboration with EndPandemics

As the pandemic spreads worldwide, companies must plan ahead and make steps that will help them protect their employees, keep their business on track, and even prepare for the worst – business disruption. Most have revisited policies, considered new innovations and platforms, and canceling events that requires mass gatherings. 

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As shops, restaurants and bars across the nation and around the world shut down to at least help flatten the curve and slow the spread of coronavirus, many workers were sent home. For most of them if not all, that means uncertainty as to when they’ll see a paycheck again.

For those who want to help, it can be hard to know where and how to start.

“There are so many ways to help and sometimes it gets very confusing as there are so many charities to choose from, but during these hard times, all kinds of giving makes a difference”, says Jennifer Rose Boadilla-Pelaez, Circularity Healthcare’s Senior Sales and Marketing Manager, Creative Director.

Circularity announced a long-term collaboration with EndPandemics on June 16th, 2020.

PROTECT AND REGENERATE

End Pandemics

In line with Circularity Healthcare’s mission to provide real and affordable healthcare, we have partnered with #Endpandemics, a global alliance to protect and regenerate nature, to help prevent future pandemics by ending the commercial trade in wild animals, expanding wild habitat, and protecting livelihoods. Your contribution will not only protect our global health and save wildlife, it will also safeguard global biodiversity, enhance sustainable agriculture, and mitigate climate change. Circularity Healthcare will also be donating its products to every member of the network of this charity to help them stay healthy.

About EndPandemics

EndPandemics is  a dynamic, global alliance of organizations—representing conservation, climate, health, finance, security, agroforestry, business, technology, and communications—who have launched this global campaign to reduce the risks of pandemics by addressing the root cause of all zoonotic outbreaks—rampant wildlife trade and the destruction of wild habitat.

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Biotech World Leader Announces Series A Fundraising on Heels of Groundbreaking COVID-19 and Phase 3 Diabetic Wound Treatment Trials

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An emerging biotech leader with operations in more than three dozen countries, Circularity Healthcare has announced its Series A fundraising campaign to raise growth capital as it prepares for its impending initial public offering. Poised to become a leader in proprietary circulatory health and noninvasive drug delivery technologies, the company has built a global infrastructure with impressive strategic partners in preparation for ramped-up manufacturing and marketing of its patented and patent-pending D’OXYVA® noninvasive rapid drug delivery devices, and D’OXYVA®-branded mini, single-use medical gas (gasotransmitter) cartridges.

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This groundbreaking transdermal system (which in human studies has been shown to significantly improve oxygen-rich blood flow) and Circularity’s new FDA-approved pharmaceutical-grade mini (14.5g) cartridges are expected to play a crucial role in the fight against COVID-19 for treating oxygen-starved, at-risk patients with underlying medical conditions. The D’OXYVA®-branded cartridges, the world’s first mini carbon dioxide cartridges approved by the U.S. FDA (and manufactured at the world’s largest specialty pharmaceutical gas producer’s FDA-audited factory in Pennsylvania), will be sold to doctors, clinics, and hospitals nationwide to treat a wide variety of conditions that can benefit from cellular and tissue oxygen therapy.

The fundraising campaign comes on the heels of Circularity’s expanded multi-year, multi-country, multi-site, Phase 3 human clinical trials led by David G. Armstrong, professor of clinical surgery at the University of Southern California’s Keck School of Medicine, and newly launched COVID-19 clinical trials led by H. Geoffrey Watson, M.D., of Oakland, California. The COVID-19 trial will focus on treating the most at-risk COVID-19 patients, 90 percent of whom suffer from low blood oxygen levels resulting from underlying conditions like diabetes, hypertension, blood pressure, cardiovascular complications, sepsis, and septic shock.

A big part of the science behind D’OXYVA® are the 2019 Nobel Prize in Physiology or Medicine-winning findings that showed how oxygen levels affect cellular metabolism and physiological function, paving the way for oxygen to be used as a promising new method to fight many diseases, including various types of cancer.

Circularity estimates that the total cost of the yearly treatments for the most critical and vulnerable millions of COVID-19 patients will amount to roughly $70 billion, and that more than 90 percent of deaths can be avoided. The company is also expected to capture a share of the COVID-19 vaccine market with its ability to deliver vaccines painlessly without needles (using its D’OXYVA transdermal delivery system) and with likely much higher efficacy. This is especially ideal for patients who are averse to needles.

Circularity is also nearing updated FDA approval because of its expanded Phase 3 diabetic foot ulcer human clinical trial. The trial has already produced promising evidence to support the safety, tolerability, and efficacy of Circularity’s patented D’OXYVA® device and pharmaceutical-grade carbon dioxide as an adjunctive treatment in speeding up the healing of diabetic foot ulcer wounds. The device uses medical-grade carbon dioxide delivered painlessly and gently through skin pores to significantly increase the oxygen-rich blood flow necessary for vital organs to function well.

“We are well-positioned right now for exceptional, immediate, and long-term growth,” says Circularity Healthcare president and CEO Norbert Kiss. “We have strategic partnerships with a combined market capitalization of over $100 billion to support our massive growth trajectory.”

“Unlike many companies in our current challenging economic climate, we have minimal debt on our balance sheets, significantly improved asset valuation, a rapidly growing customer base, and an established, large supply chain virtually all inside the United States, propelled by massive demands for many years to come, with an estimated current inventory retail value of millions of dollars,” says Norbert .

The growing demand for home healthcare and point-of-care options is expected to trigger a rise in demand for packaged medical-grade gases and equipment. The global medical gas market was valued at $7.5 billion in 2016 and is expected to witness a CAGR of 9 percent during the forecast period until the year 2024.

Due to growing concerns about aging, obesity, and diabetes, Research and Markets in December 2017 estimated that the global market for chronic wound care equipment would grow from $18 billion in 2017 to $22 billion by 2022. The United States accounts for 35-40 percent of the global market and is expected to grow at 7 percent CAGR. In contrast, D’OXYVA’s mass-market adoption will offset billions of unwanted healthcare expenditure, considering that a single diabetic foot ulcer standard of care in the United States annually costs about $30,000 in indirect and direct costs on average per person.

Eighty percent of cases still result in amputations, and 80 percent of amputees die within three years of amputation. This is the potential future for about 10 million people if D’OXYVA treatment is not adopted. Circularity’s Phase 3 human diabetic foot ulcer clinical trial centers on healing diabetic foot ulcers at one-tenth of the time and cost of competing modalities, while achieving zero reports of adverse side effects after eight years.

“We can produce devices for 100 million households and cartridges in various sizes for over 300 million people within 18 months with our dedicated production lines,” says Kiss. “Furthermore, Circularity is exploring the opportunity to work with the U.S. government to make the initial millions of applications widely available and affordable to those who need it most. This could generate roughly $50 billion in sales revenue from devices and $70 billion in sales of our drugs.”

The company’s clinical trials are led by some of the most respected medical professionals at top universities in the country, including the University of Southern California, Harvard University, Northwestern University, and Drexel University College of Medicine. Additionally, Circularity is represented by the leading FDA team at K&L Gates LLP (Circularity’s main global, corporate, regulatory, and IP law firm since its inception) and works closely with regulatory teams from the world’s largest specialty pharmaceutical gas producers.

D’OXYVA® is currently available for use in hospitals and at home (over the counter) through its Investigational Device Exemption status under FDA regulations. The company has seen impressive growth volumes over the past two months, with pending orders from some of the largest hospitals and healthcare networks around the world for its regulated D’OXYVA®-branded products, and an 86 percent repeat customer rate for orders of its over-the-counter products.

“This is in line with our original scheduled launch of our comprehensive PR, sales, and marketing campaigns, combined with the anticipated release of our clinical evidence,” says Joel Ellis, national VP of sales. “We have been aggressively expanding sales operations by continually hiring new sales representatives in virtually all areas of our business.”

Along with adding to its sales team, Circularity is launching half a dozen new clinics with leading doctors this week, with plans to multiply those new clinics to expand to hundreds of locations nationwide within the coming months.

The Series A fundraising is open to venture capitalists, private equity investors, qualified institutional buyers, angel investors, and angel investor groups. Potential investors can contact the company directly at (626) 817-6698. For more information on the clinical trials, please visit – https://doxyva.com/covid-19/.

Forward-Looking Information:
This press release may contain forward-looking information. This includes, or may be based upon, estimates, forecasts and statements as to management’s expectations with respect to, among other things, the quality of the products of Circularity Healthcare, LLC, its resources, progress in development, demand, and market outlook for non-invasive transdermal delivery medical devices. Forward-looking information is based on the opinions and estimates of management at the date the information is given and is subject to a variety of risks and uncertainties that could cause actual events or results to differ materially from those initially projected. These factors include the inherent risks involved in the launch of a new medical device, innovation and market acceptance uncertainties, fluctuating components and other advanced material prices, new federal or state governmental regulations, the possibility of project cost overruns or unanticipated costs and expenses, uncertainties relating to the availability and costs of financing needed in the future and other factors. The forward-looking information contained herein is given as of the date hereof and Circularity Healthcare, LLC assumes no responsibility to update or revise such information to reflect new events or circumstances, except as required by law. Circularity Healthcare, LLC makes no representations or warranties as to the accuracy or completeness of this press release and shall have no liability for any representations (expressed or implied) for any statement made herein, or for any omission from this press release.

About Circularity Healthcare, LLC
Headquartered in Pasadena, California, Circularity Healthcare is an emerging biotech leader around the world in proprietary circulatory health and noninvasive skin delivery technologies. Since 2011, the company has been committed to radically changing the standard of care and improving lives by developing, manufacturing, and marketing affordable medical devices and pharmaceutical products to promote consumer health and wellness. For more information, please visit https://doxyva.com.

About Norbert Kiss
CEO and Co-Founder Norbert Kiss leads the Circularity Healthcare team, and spearheaded the development of the company’s technology and business platforms. Norbert has nearly a quarter of a century of executive and entrepreneurial experience, both domestically and in more than 60 countries involving startups; think and do tanks; and large brands in technology, intellectual property, regulatory affairs, and sales and marketing. He has been involved in the transdermal and cardiovascular space for more than a decade.

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New COVID-19 Clinical Trial Announced To Treat Over 90% of Patients With Underlying Medical Conditions

A new clinical trial is being announced today that could significantly increase the rate of recovery for COVID-19 patients with underlying health conditions and save lives! Circularity Healthcare’s trial will help some of the most at-risk patients suffering from complications due to diabetes, poor circulation, hypertension, cardiovascular disease and high blood pressure. The trial will involve the use of Circularity’s already FDA-approved drug and IDE device D’OXYVA® (deoxyhemoglobin vasodilator) – a non-toxic, non-invasive microcirculation transdermal device.  It is the first biotech solution of its kind to improve overall oxygen-rich blood flow. The device has been shown to significantly heal diabetic wounds, reduce the risks of amputations, prevent sepsis and septic shock,  improve blood pressure and general vital organ function of the pancreas, liver, brain and kidneys, while increasing overall health for some of the most vulnerable patients. 

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“Anyone who suffers from an underlying condition should know that this proven treatment option is available,” says Circularity Healthcare CEO Norbert Kiss. “Every medical report released so far shows that severe COVID-19 patients need blood oxygenation and blood thinners. The overwhelming majority of patients have diabetes and cardiovascular issues beyond pulmonary complications and they all have sepsis setting in early on. These are the exact main vitals and chronic diseases D’OXYVA improves like no other medication currently available on the market.”

The recommendation for this new treatment is based on the following:

  • After eight years of three dozen human studies with leading experts at some of the most prestigious universities and hospitals in the world (including Penn State and Airlangga University), zero adverse effects were reported. D’OXYVA is currently expanding its Phase 3 trial with Professor David G. Armstrong and his colleagues.
  • The pharmaceutical-grade CO2 utilized by the D’OXYVA device has already been approved by the FDA (it is the same CO2 drug already readily available in every hospital and provided by the same supplier). There is just a 1-2 week IRB approval to launch the trials at any location due to the investigational device exemption (IDE) status of D’OXYVA. Additionally, with the device factory S.-based in Fremont, CA, all the regulated products are also readily-available to launch the trial.
  • The effects of transdermal CO2 have been widely noted in wound care as demonstrated in clinical studies. Healing, closure, prevention against sepsis and septic shock and recovery of an ulcer (non-healing) due to diabetes and cardiovascular complications are much faster and often successful where other modalities have failed.
  • All research projects performed up to date have consistently recorded a significant decrease in systolic blood pressure (from the heart) and diastolic (return to the heart) blood pressure. These results have been consistent throughout all study time periods   up to 240 minutes (the longest time period evaluated after treatment).
  • Systemically, CO2 therapy has shown great success to improve the healthcare of patients with high blood pressure, general vital organ function of patients with high blood pressure, and general vital organ function like that of the pancreas, liver, brain, and kidneys

The clinical trials are now waiting IRB approvals and are about to launch under existing contracts at multiple sites including top U.S. universities such as Harvard, Yale, M.I.T, USC, and UCLA, with more physicians and patients being invited to participate. Since the product can be monitored at home, potential patients do not have to be currently admitted to a hospital in order to take part in the trial. For more information on the trial or to sign up, please visit https://doxyva.com/covid-19/ or call 626.240.0956.

About Circularity Healthcare, LLC
Circularity Healthcare, LLC, located in Los Angeles, CA, is a private biotech and MedTech products and services company that designs, makes, markets, sells, distributes, and licenses its patented and patent-pending technologies, such as its flagship non-invasive deoxyhemoglobin vasodilator product line, D’OXYVA®. One of the main mechanisms underlying D’OXYVA’s science received the Nobel Prize for Medicine in 2019. Circularity enters into exclusive agreements with manufacturers to launch products in large and small clinics and hospitals to help enhance their profits and credit profiles with a wide variety of advanced products and services. In addition, Circularity Healthcare assists in the financing of equipment, working capital, and patient financing at industry-leading terms and speed.

For more information, please visit http://www.circularityhealthcare.com or http://doxyva.com; doctors (Rx only) visit http://wound.doxyva.com and send your general inquiries via the Contact Us page. For specific inquiries, contact Circularity Customer Care at info(at)doxyva(dot)com, info(at)circularityhealthcare(dot)com, or by phone (toll free) at 1-855-5DOXYVA or 1-626-240-0956.

Forward-Looking Information
This press release may contain forward-looking information. This includes, or may be based upon, estimates, forecasts and statements as to management’s expectations with respect to, among other things, the quality of the products of Circularity Healthcare, LLC, its resources, progress in development, demand, and market outlook for non-invasive transdermal delivery medical devices. Forward-looking information is based on the opinions and estimates of management at the date the information is given and is subject to a variety of risks and uncertainties that could cause actual events or results to differ materially from those initially projected. These factors include the inherent risks involved in the launch of a new medical device, innovation and market acceptance uncertainties, fluctuating components and other advanced material prices, new federal or state governmental regulations, the possibility of project cost overruns or unanticipated costs and expenses, uncertainties relating to the availability and costs of financing needed in the future and other factors. The forward-looking information contained herein is given as of the date hereof and Circularity Healthcare, LLC assumes no responsibility to update or revise such information to reflect new events or circumstances, except as required by law. Circularity Healthcare, LLC makes no representations or warranties as to the accuracy or completeness of this press release and shall have no liability for any representations (expressed or implied) for any statement made herein, or for any omission from this press release.

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Join Professional Fitness Icon Eva Marie in a 30-Day D’OXYVA Challenge

Former professional wrestler, actress, and fitness model Eva Marie recently announced a 30-day challenge based on a daily application of D’OXYVA. In a five-minute video on her Instagram page, she and her husband announced that they would both be testing the product to determine the impact on their health and vitality. Marie and the makers of D’OXYVA are also hosting a contest in which her followers can enter to win their own 30-day challenge package.

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Having been an athlete most of her life, Eva Marie has always been a natural fitness enthusiast. After winning the 2012 Powertech Model competition, she joined the WWE in May 2013. Through her time as a wrestler, manager, and actor with the Total Divas, she has always strived for maximum fitness. In recent years, she and her husband have launched social media channels focusing on fashion and fitness and helmed a number of entrepreneurial enterprises, including the Natalie Eva Marie X Ryderwear fashion collection and NEM Fit workout program.

30-Day D’OXYVA Challenge

In part because of the COVID-19 pandemic, Eva Marie and her husband decided to spend their physical distancing time experimenting with various health and wellness programs. Beginning April 17, 2020, the couple decided to use D’OXYVA for the next thirty days and report the results to her fans. To better understand the impact, they will take a few baseline health measurements, such as blood oxygen levels. After the challenge, they will take more measurements to provide anecdotal and statistical comparisons. The video also demonstrates the non-invasive application of the D’OXYVA product.

Why D’OXYVA?

D’OXYVA is a revolutionary new application providing a number of powerful health benefits. At its core, the five-minute, noninvasive application exposes the body to a painless vapor of purified CO2 molecules across the skin. The body responds to this exposure by increasing circulation to the affected areas. Improvements in microcirculation have been proven to lead to a number of positive health outcomes, including greater healing and immune responses.

D’OXYVA has been shown to eliminate nearly all spider and varicose vein markings and speed the healing of open wounds. Improvements in blood flow and nerve stimulation can relieve chronic pain from conditions such as neuropathy or advanced diabetes. As an added benefit, D’OXYVA is a single product that can replace a number of treatments for various conditions. Users can save money and time by consolidating therapies into one application.

Benefits for Healthy People

D’OXYVA is not just for people suffering from chronic conditions. Daily use of D’OXYVA can also provide improvements in circulation and potentially produce benefits related to general fitness, cardiovascular efficiency, and endurance. Eva Marie’s 30-day challenge is intended to allow her to experience and chart these results for the general public, and Marie and the makers of D’OXYVA want to share these benefits with you!

Two lucky people will receive a complete month’s supply of D’OXYVA, including cartridges and the oximeter, to measure blood oxygen levels. Winners will be chosen at random on Monday, April 20, 2020. To enter your name:

 

For More Information:

Don’t wait to join Eva Marie in her 30-day challenge of D’OXYVA! Even if you don’t win, visit https://doxyva.com/shop/ today for great deals on equipment and supplies. You can find sales of up to 35% off for a limited time only!

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Non-Invasive Microcirculatory Device Could Help COVID-19 Patients With Underlying Medical Conditions

covid 19

Read article in PRWeb

According to the CDC, nearly 90% of Americans being hospitalized with COVID-19 have an underlying medical condition. Healthcare technology company Circularity Healthcare, creators of D’OXYVA®, is looking to help these patients treat those conditions faster to better their chances of recovery. D’OXYVA® (deoxyhemoglobin vasodilator), the first biotech solution of its kind, provides non-invasive, transdermal microcirculation to improve overall oxygen-rich blood flow – an effective treatment option for a variety of conditions including diabetes, hypertension, cardiovascular issues, COPD, and high blood pressure.

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“D’OXYVA is aimed at helping millions of people improve their health and their immune response,” says Circularity Healthcare CEO Norbert Kiss. “We are confident this device can save lives in the fight against the Coronavirus by helping repair the body’s functions in people with underlying conditions.” D’OXYVA speeds up the body’s healing process by improving micro and macro circulation and the autonomic nervous system (ANS), detoxifying the liver and kidney, reducing inflammation, and increasing oxygenation and delivery of nutrients. It is the only clinically-tested, non-invasive, portable, transdermal microcirculatory regenerative solution device.

The over-the-counter product is intended to ease the expense and inconvenience of time-consuming doctor visits by offering affordable and effective management of conditions that can take place in the comfort of your own home. “This is truly the future of optimized healthcare,” says Kiss. “D’OXVYA provides an advanced technology that offers a painless solution to help people manage chronic health conditions and see measurable results within a matter of weeks. This is a great way to save time and money by reducing the reliance on opioids and other expensive medications and office visits.”

Extensive clinical research conducted over an eight-year period has already shown incredible success rates. Trials have included over three dozen human clinical studies including double-blind, randomized, and placebo-controlled studies at Pennsylvania State University. The company is now significantly expanding Phase 3 human clinical trials working with the top ten universities in the U.S. targeting underlying conditions specific to COVID-19 risk factors such as oxygen-rich microcirculation in lungs, the heart, kidneys and other vital organs as well as inflammatory markers.

The science used to create the device received a 2019 Nobel Prize in Physiology Medicine. D’OXYVA works by utilizing FDA-cleared, non-toxic molecules (over-the-skin deoxyhemoglobin vasodilator) that deliver a vapor of pharmaceutical-grade CO2 and water to the peripheral microcirculation. This vapor is delivered through the placement of the D’OXYVA device over the thumb for a 5-minute period. The CO2 then travels into the microcirculation of the skin, where it causes a vasodilation that leads to increased perfusion. Since its introduction in 2012, the physician-recommended, easy-to-use device has helped users track and regain their health by repairing or growing new vessels and significantly improving nerve activities in the body.

“The fact is that D’OXYVA increases the effectiveness of the Microcirculatory System,” says Dr. Jim Bledsoe, PHD and Holistic Practitioner. “Increasing the blood flow will help the body improve itself.”

D’OXYVA is currently available OTC online.

The company is actively accepting donation requests from nurses and doctors to provide D’OXYVA for immediate lifesaving treatment of hospital patients in critical condition due to its Investigational Device Exemption (IDE) status under FDA regulations. For more information, please visit doxyva.com/covid-19 or call 626.817.6698.

About Circularity Healthcare, LLC Circularity Healthcare, LLC, located in Los Angeles, CA, is a private biotech and MedTech products and services company that designs, makes, markets, sells, distributes, and licenses its patented and patent-pending technologies, such as its flagship non-invasive deoxyhemoglobin vasodilator product line, D’OXYVA®. One of the main mechanisms underlying D’OXYVA’s science received the Nobel Prize for Medicine in 2019. Circularity enters into exclusive agreements with manufacturers to launch products in large and small clinics and hospitals to help enhance their profits and credit profiles with a wide variety of advanced products and services. In addition, Circularity Healthcare assists in the financing of equipment, working capital, and patient financing at industry-leading terms and speed. For more information, please visit http://www.circularityhealthcare.com or http://doxyva.com; doctors (Rx only) visit http://wound.doxyva.com and send your general inquiries via the Contact Us page. For specific inquiries, contact Circularity Customer Care at info(at)doxyva(dot)com, info(at)Circularity Healthcare(dot)com, or by phone (toll free) at 1-855-5DOXYVA or 1-626-240-0956. Forward-Looking Information This press release may contain forward-looking information. This includes, or may be based upon, estimates, forecasts and statements as to management’s expectations with respect to, among other things, the quality of the products of Circularity Healthcare, LLC, its resources, progress in development, demand, and market outlook for non-invasive transdermal delivery medical devices. Forward-looking information is based on the opinions and estimates of management at the date the information is given and is subject to a variety of risks and uncertainties that could cause actual events or results to differ materially from those initially projected. These factors include the inherent risks involved in the launch of a new medical device, innovation and market acceptance uncertainties, fluctuating components and other advanced material prices, new federal or state governmental regulations, the possibility of project cost overruns or unanticipated costs and expenses, uncertainties relating to the availability and costs of financing needed in the future and other factors. The forward-looking information contained herein is given as of the date hereof and Circularity Healthcare, LLC assumes no responsibility to update or revise such information to reflect new events or circumstances, except as required by law. Circularity Healthcare, LLC makes no representations or warranties as to the accuracy or completeness of this press release and shall have no liability for any representations (expressed or implied) for any statement made herein, or for any omission from this press release.
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Always Ready to D’OXYVA, Never Have to Order

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.
Circularity Healthcare’s Autopay-Autoship Program means your D’OXYVA supplies are always on-hand right-here, right-now.
You already know that D’OXYVA’s daily continued application for at least 8 weeks has been proven to deliver greater results for your physical restoration and mental renewal for an enhanced overall quality of life.

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Now you can skip the website, cart and checkout process and receive a 6-month supply of D’OXYVA Easytwist cartridges delivered directly to your doorstep automatically — plus, enjoy FREE shipping on your order and savings up to $360 off the regular order price.

Circularity Healthcare’s D’OXYVA Autopay-Autoship Program includes 6 months of D’OXYVA supplies for $179 per month, payable with any major banking card or your PayPal account.

This convenient, reliable, and affordable program, now in its second decade of operation, was born of Circularity Healthcare’s unwavering commitment to serving its customers with the utmost care and support.

“We never stop thinking about our customers satisfaction — this program is only one of the many programs we have in place that our customers can choose from that will fit to their needs,” says Jennifer Boadilla-Pelaez, Senior Sales and Marketing Manager, and Creative Director of Circularity Healthcare.

For more information and to start your Circularity Healthcare’s D’OXYVA Autopay-Autoship Program, click the button below.

HOW D’OXYVA CAN HELP?

D’OXYVA is the only fully noninvasive, completely painless over-the-skin microcirculatory and nerve stimulant solution that has been validated to significantly improve microcirculation.

The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.

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D’OXYVA® improves dermal microcirculation and promotes wound healing in the diabetic foot (clinical trial update)

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Prof. Puruhito and colleagues have released the results of three observational trials showing that D’OXYVA® (Circularity Healthcare LLC), a deoxyhemoglobin vasodilator, improves vasodilation in the treatment of diabetic foot ulcers (DFUs), boosts dermal microcirculation, and helps in the healing process of DFUs.

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Published in PRWeb

D’OXYVA® is a validated circulatory and nerve stimulant. The system was used by Prof. Puruhito for CO2 transdermal delivery, which has been shown to produce higher oxygen unloading by hemoglobin, thereby increasing oxygen-rich blood flow in the local microcirculatory system1. This improved dermal microcirculation leads, in turn, to enhanced wound healing2.

The American Diabetes Association standards of care for DFUs refer to microvascular complications and their treatment via improvements in microcirculation; therefore, Prof. Puruhito’s team set out to test CO2 transdermal delivery via D’OXYVA® in their patients. They have been gathering data since 2015, which led to the following results.

During the course of a 5-day treatment, O2 saturation increased in patients treated with transdermal CO2 in comparison to controls (15 patients/group)3 over the whole measurement range (up to 120 minutes post application). Moreover, a consistent heart rate decrease was found in patients undergoing transdermal CO2 treatment. Furthermore, the perfusion index (PI) showed an upwards tendency in the treatment group, whereas it remained stable for untreated controls. See figure 1.

diabetic wound

Figure 1: Changes observed after a 5-day transdermal CO2 treatment with D’OXYVA®. H1-H5: pre-treatment, 10, 30, 60, 90, and 120 minutes after; blue trace: control, orange trace: treatment. (A) Changes in O2 saturation (B) Decrease in heart rate due to treatment (C) Masimo® measurements of PI.

In light of these results, Prof. Puruhito’s team performed extra measurements of transcutaneous carbon dioxide (TcPCO2), O2 saturation, and PI in the 15 patients treated with D’OXYVA® for transdermal CO2 delivery3–5. This data show that the oxygen saturation reached almost 100% in some patients, whereas the TcPCO2 remained relatively stable throughout the treatment time (120 minutes). For more detailed information, see figure 2.

Figure 2: Transcutaneous CO2 pressure (TcPCO2), O2 saturation, and PI assessment in the 15 patients subjected to transdermal CO2. (A) SENTEC TcPCO2 measurements for all patients at various time points after D’OXYVA® application (pre-treatment, 5, 60, 90, and 120 minutes after) (B) O2 saturation (C) PI.

Finally, Prof. Puruhito’s team demonstrated the positive effects of transdermal CO2 delivery via D’OXYVA® on the healing of DFUs5 (fig. 3), proving the clinical potential of this intervention to improve the quality of life of people suffering from this common complication of diabetes.

Figure 3 Wound healing after 5-day treatment with transdermal CO2 delivery via D’OXYVA® in cases of DFU Wagner-1 and Wagner-2

In conclusion, the use of a D’OXYVA® device for transdermal CO2 delivery improves the outcomes of DFUs by enhancing dermal microcirculation and increasing perfusion rates and tissue oxygenation, therefore assisting in the healing process of the ulcers typical of diabetes neuropathy.

ABOUT PROF. ITO PURUHITO

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Ito Puruhito, MD is professor in the Department of Thoracic and Cardiovascular Surgery at Dr. Soetomo General Hospital as well as a senior lecturer in the Faculty of Medicine at Universitas Airlangga (Indonesia). From 2001 to 2016, he was the rector of the aforementioned university. Prof. Puruhito finished his medicine studies at Universitas Airlangga in 1967, and in 1972 he received a doctorate degree, graduating cum laude from Frederich-Alexander University (Erlangen-Nürnberg, Germany). In his native country, he developed the Department of Thoracic-Cardiovascular Surgery at his former university, Universitas Airlangga, Surabaya. In 1978, he co-founded the Indonesian Association of Thoracic, Cardiac and Vascular Surgery. Prof. Puruhito has authored numerous indexed research articles in Scopus, ISI-Thompson or PUBMED, and scientific presentations and written several books in Indonesian, English, and German. He acted as reviewer for peer-reviewed journals such as Medical Tribune, Annals of Thoracic and Cardiovascular Surgery, Asian Annals of Surgery, Medicinus, and many more Indonesian medical-surgical journals. Currently, apart from lecturing, Prof. Puruhito actively researches stem cells, cardiovascular medicine, and surgery at the Institute of Tropical Disease as well as some work in microcirculation. Further, he acts as coordinator of research affairs at the Department of TCV-Surgery at Dr. Soetomo General Hospital Surabaya. Since 2014, he has been the chairman of the Council of Research in the Ministry of Research Technology and Higher Education of the Republic of Indonesia.

ABOUT D’OXYVA

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

D’OXYVA® (deoxyhemoglobin vasodilator) is a novel, clinically validated blood flow and nerve stimulant for people suffering from neuropathy. In various clinical trials, D’OXYVA® has validated leading independent research results and demonstrated above-average results in improving a host of physiological functions.

Subjects suffering from high blood sugar have reported neuropathy pain relief minutes after D’OXYVA® was administered and long-term blood sugar level improvements after just a few weeks.

Rapid and gentle skin delivery (over-the-skin) with the D’OXYVA® lightweight, handheld device has prompted improvements in blood microcirculation or PI by 33%* on average in all participants. Lasting results have been measured at 5-60 minutes and up to 4 hours after a single 5-minute D’OXYVA® delivery on the skin surface without reduction in PI levels.6

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Circularity Healthcare, LLC Receives 2019 Pasadena Award

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Pasadena Award Program Honors the Achievement

PASADENA November 30, 2019 — Circularity Healthcare, LLC has been selected the 2nd time in 3 years for the 2019 Pasadena Award in the Healthcare Products Developer and Manufacturer category by the Pasadena Award Program.

Each year, the Pasadena Award Program identifies companies that we believe have achieved exceptional marketing success in their local community and business category. These are local companies that enhance the positive image of small business through service to their customers and our community. These exceptional companies help make the Pasadena area a great place to live, work and play.

Various sources of information were gathered and analyzed to choose the winners in each category. The 2019 Pasadena Award Program focuses on quality, not quantity. Winners are determined based on the information gathered both internally by the Pasadena Award Program and data provided by third parties.

About Pasadena Award Program

The Pasadena Award Program is an annual awards program honoring the achievements and accomplishments of local businesses throughout the Pasadena area. Recognition is given to those companies that have shown the ability to use their best practices and implemented programs to generate competitive advantages and long-term value.

The Pasadena Award Program was established to recognize the best of local businesses in our community. Our organization works exclusively with local business owners, trade groups, professional associations and other business advertising and marketing groups. Our mission is to recognize the small business community’s contributions to the U.S. economy.

SOURCE: Pasadena Award Program

CONTACT:
Pasadena Award Program
Email: PublicRelations@online-best-advisory2019.org
URL: http://www.online-best-advisory2019.org

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Innovative Collaboration: The Cutting Edge of Medicine Goes “Behind The Scenes”

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

LOS ANGELES (PRWEB) DECEMBER 11, 2019

Circularity is partnering with Telly Award-Winning “Behind the Scenes” to provide regular, ongoing, high-quality content from leading experts in a variety of fields with an initial focus on microcirculation science, regenerative medicine, and advanced wound healing and related symptoms. The show reaches 60 million households domestically.

“Behind The Scenes with Host Laurence Fishburne” is a public television icon that has won numerous awards and delivers precision idea-telling at its best. Circularity is an innovative healthcare organization that is health-bent on their trademarked slogan: “Improving Lives by Improving Blood Flow.” Their coming together to bring forward the ideas of modern health science on a stellar entertainment platform can only make for riveting content going forward. Viewers will find themselves in a win-win situation.

Watching informative content via this stylized venue will leave viewers feeling quite satisfied with their television watching experience. It is time well spent and information precisely delivered.

A Little More About Circularity

Circularity is concerned with bringing the very best in Health care innovation to the public. In so doing, they have manufactured a product called D’OXYVA. This product has a two-pronged approach to health. First, it can be quite effective in reducing the debilitative effects of many of the diseases that are affecting the world today, such as COPD, diabetes, and cardiovascular illnesses. Secondly, Circularity’s D’OXYVA can be used in a preventative capacity to improve microcirculation. The concept of microcirculation has far-reaching implications in neurology, oncology, endocrinology, cardiovascular health, respiratory health, dermatology, diabetic wound healing or diabetic wound care and other major fields.

What “Behind The Scenes with Host Laurence Fishburne” Will Bring to the Table

Behind The Scenes has been an innovator in bringing information to the forefront in the public television space. The award-winning series features segments on the newest technologies, as well as fresh takes on existing entities, phenomenon, and natural occurrences. The show’s website boasts that the television series “highlights the evolution of education, medicine, science, technology and industry through inspiring stories.”

Aside from the Emmy-winning and Academy Award nominated actor Lawrence Fishburne as host, the program has an award-winning creative development team. Viewers walk away with a rich knowledge of the subject. Viewers may have known about this subject their whole lives, or it may be about something completely new. Viewers learn an evolving aspect of the topic which keeps the perspective fresh.

The dawning of a new age has appeared with this collaboration. Individuals who want to know more about what the health science field is bringing into our hospitals and doctors’ offices will not be disappointed. In today’s world, it is imperative that we are advocates for our own health.

Coming Soon: Miami ReLife’s Dr. Steven Gelbard

The first series is with Dr. Steven Gelbard, a nationally-famed authority with his ReLife Miami Institute on stem cells. Dr. Gelbard presents D’OXYVA’s Nobel Prize-winning science as a regenerative medicine. Dr. Gelbard is involving his direct contacts with top NFL players and other top sports celebrities in the monthly series, along with 25—40 top neurosurgeons and other experts working under ReLife.

Imagine having the ability to receive D’OXYVA and other innovative treatments and non-invasive procedures for chronic wound care amid the luxury of a five-star hotel. Behind The Scenes guest, Dr. Gelbard, a Tufts School of Medicine educated neurosurgeon, makes it happen right now. Medicine has left the hospital building and has become the proactive choice of the health conscious. We can all look forward to learning more about how to live a healthier and more informed lifestyle from this awe-inspiring episode.

According to Norbert Kiss, President and CEO of Circularity Healthcare, this collaboration is door busting. Mr. Kiss tells us, ”[We] can offer unprecedented access to this amazing Emmy-winning show called Behind the Scenes with very amazing terms due to our strategic involvement. We welcome any expert.”

Laurence Fishburne, host of Behind The Scenes,” beckons, “Join me as we all discover the endless ways to enjoy the skills and imagination.”

Don’t miss the evolution. It’s being televised. Circularity and Behind The Scenes—Stay tuned for a mind-fortifying experience!

Circularity Values:

We, at Circularity believe in a long-sought-after goal in health care; people should have access to one health application that solves most of their short and long term health issues without compromising other aspects of their health while doing this quickly, affordably, and without pain.
Circularity develops, manufactures and markets advanced technologies that significantly improve quality of life by improving some of the most essential physiological functions in the body.

About Behind The Scenes With Laurence Fishburne

Behind The Scenes is an award-winning program that highlights new stories and innovative concepts through groundbreaking short-form and long-form documentary presentation. The program, which is anchored by a veteran production team with decades of industry experience, is able to effectively communicate the most critical stories to a wide and diverse audience.

Behind The Scenes with Laurence Fishburne, has established an impressive and heralded career, amassing over one-hundred credits across the varied platforms of stage, television and film. He’s well known for major for roles in such films as; John Wick 2, Fantastic 4 Rise of the Silver Surfer, Mission Impossible III, Mystic River, Boyz n the Hood, What’s Love Got to Do With It, and Apocalypse Now. On the small screen, the award-winning and versatile actor played compelling roles in shows such as CSI: Crime Scene Investigation, CSI: Miami, CSI: New York and Hannibal. The Behind The Scenes Actor currently stars as Pops on the hit TV comedy Black-ish.

About Circularity Healthcare, LLC

Circularity Healthcare, LLC, located in Los Angeles, CA is a private biotech and MedTech products and services company that designs, makes, markets, sells, distributes and licenses its own patented and patent pending technologies, such as its flagship non-invasive deoxyhemoglobin vasodilator product line, D’OXYVA®. One of the main mechanisms underlying D’OXYVA’s science received the Nobel Prize for Medicine in 2019. Circularity enters into exclusive agreements with manufacturers to launch products and with large and small clinics and hospitals in order to help them enhance their profits and credit profiles with a wide variety of advanced products and services. In addition, Circularity Healthcare assists in the financing of equipment, working capital and also patient financing at industry-leading terms and speed.