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The Anatomy of Chronic Pain – PART 1

Are you in pain? Have you been looking for ways to be pain-free? Do you understand your pain?

A profound understanding of chronic pains requires an in-depth deconstruction of the nervous system. The nervous system is very complicated; nerves make it possible for the nervous system to send messages to and from the medulla/brain.

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PROFOUND KNOWLEDGE OF CHRONIC PAIN

The central nervous system consists of the brain and the spinal cord. The peripheral nervous system is somewhat like a branch-off of the spinal cord, and the peripheral and central nervous systems can be affected by neuropathic pain.

The type of pain that arises as a result of a malfunction in the nerves is referred to as neuropathic pain. The peripheral nervous system has 31 roots that spread from the spinal cord to various parts of the body.

These nerves make it possible for us to feel and move; those responsible for feelings are the sensory nerves, while those responsible for movement are the motor nerves. The spinal cord has various levels, and each has multiple spinal nerves attached.

The cervical level has eight pairs, the thoracic has 12 pairs, the lumbar has five pairs, the sacral has five pairs, and the coccyx has just a pair. The peripheral nervous system is further broken into two categories, namely the somatic and autonomic nervous systems.

The autonomic nervous system is responsible for controlling involuntary actions in the body, making it possible for the heart to function effectively and for us to digest our food without having to think about it.

The somatic nervous system, on the other hand, has nerves that pass to the skin and the musculoskeletal network: bones, ligaments, tendons, muscles, etc. These nerves allow us to feel pain.

If any nerve in our body is sprained or damaged, we develop chronic pain; damaged nerves send an unending stream of pain messages to the brain.

Another essential part of our nerves known as a nociceptor. Understanding certain types of chronic pains requires knowledge about these nociceptors, which are located at our nerve endings activated whenever something triggers pain.

If, peradventure, you got your fingers closed in the car door, the nociceptors in your fingers would be and send a message of pain to the spinal cord and brain through the peripheral nerves.

However, seconds before you slammed your fingers, the nociceptors weren’t activated—why? Because there was no stimuli (or injury) to make the nociceptors respond.

Taking this information into account allows the conclusion that one primary cause of chronic pain is malfunctioning nociceptors; even when there are no direct causes for the pain, nociceptors can still send continuous pain messages to the brain.

Let’s consider the example we used earlier; assume the fingers that got slammed by the car doors were healed, but for some strange reason, you’re still feeling a lot of pain. It may be that the nociceptors located in your hand are malfunctioning.

That is, they’re still sending continuous pain messages to the brain, which could bring about chronic pain.

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Rediscover Your Freedom with the Best-Kept Secret in Neuropathic Solution

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Life is short; the very luckiest among us will live to see seven or eight decades. Unfortunately for many people, years of life don’t always translate to actually living. If you suffer from neuropathic pain, for example, you may experience far too much pain and discomfort to travel, work, or play. If this sounds like your life, a non-invasive alternative solution may just provide the key to simplifying your pain regimen.

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Madison, a 55-year-old mother from Los Angeles, CA, has been suffering from neuropathic pain for almost 5 years now. She was diagnosed with type 2 diabetes when she was 40 years old, and due to being unable to afford all of her medications, she started to develop complications ranging from chronic foot ulcers to neuropathic pain. She was introduced to a non-invasive alternative solution backed by a Nobel prize-winning science to provide significant relief from her neuropathic pain and help her save money while improving her quality of life and reducing the risk of further complications.

Risks of Invasive Procedures

In most cases, medical professionals have to weigh the benefits of applications against the potential risks involved. They may even select a solution that is less effective for a condition because it is far less dangerous. Accordingly, non-invasive options that actually work can be a great choice for relevant conditions.

Minimally invasive surgery is accomplished using smaller incisions and therefore requires less recuperation time. Although it is generally considered safer, it still comes with risks related to anesthesia. In addition, any procedures that break the skin risk bleeding and infection (Mayo Clinic).

If you are already dealing with existing pain and mobility issues, you want to feel better, not worse. Why start with an application that can lead to potential infections or extend your recovery time? As a completely non-invasive application, D’OXYVA helps people potentially enhance the healing process without the risk of invasive procedures.

Multiple Symptom Application

According to the AARP, the average person 45 or older in the US takes at least four prescription medications every day. While such an involved regimen can be helpful in getting people back to living their lives, it can also be stifling. Each of those prescriptions costs money, and even the copays can get expensive.

Remembering to take each of the medications at the right time can also get confusing. There are pills to take at night and others to take in the morning. Certain solution can only be administered on an empty stomach, while others require a full meal. Of course, with each combination of application, there is always the potential for problems with drug interactions. Considering the money and time spent, patients can begin to wonder if it is all worth it.

That is why an application that addresses root causes can be a great find. D’OXYVA, for example, is designed to improve both micro- and macrocirculation within the body. That makes it a powerful tool to address a wide variety of conditions that allows you to save money and time by simplifying your healing and pain-relieving procedures. More money and more time mean more freedom to live your everyday life to the fullest.

Ask Your Doctor About D’OXYVA

D’OXYVA is completely noninvasive and effective against a variety of problems. By addressing the root cause of circulation difficulties, D’OXYVA helps eliminate the appearance of varicose veins and significantly reduces healing time for diabetic wounds in addition to its unparalleled record of alleviating many forms of neuropathic and chronic pain without addiction. Contact your doctor today and ask about D’OXYVA.

HOW D’OXYVA CAN HELP?

D’OXYVA is the only fully noninvasive, completely painless over-the-skin microcirculatory and nerve stimulant solution that has been validated to significantly improve microcirculation.

The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.

Reduce unwanted doctor visits, recommended and ranked top by experts!

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7 Things You Should Know About Diabetic Foot Care

diabetes success story

Diabetes can lead to complications[1] involving the feet, including peripheral neuropathic pain, diabetic foot ulcers, poor circulation, decreased sensation and increased callus formation. This can lead to skin breakdown and the formation of ulcers that can become infected and even lead to amputations. Proper diabetic foot care can decrease the risk of developing these complications. Read on to learn about the case of Chase L., who suffered from severe diabetes with complications involving both feet and who experienced significant pain relief through the application of the non-invasive deoxyhemoglobin vasodilator D’OXYVA[2]

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Chase was a 64-year-old male patient with a 7-year history of type 2 diabetes mellitus. He had high blood sugar levels for a 3-year period before his diagnosis, as well as a history of elevated cholesterol and triglycerides and high blood pressure. On laboratory testing, Chase had an A1C level of 8.3% (normal A1C levels are less than 5.7%) and a blood sugar reading of 186 (normal readings are 70-110). 

On physical exam, Chase exhibited ingrown toenails, pallor of the feet, cyanosis of the toes and thick callus formation of the heels. In addition, he had decreased sensation over the dorsum of both feet and diminished pedal pulses bilaterally. After spending thousands of dollars on medications and trying various non-invasive treatments without relief, Chase experienced significant pain relief and a decrease in the cyanosis of his toes after 6 weeks of daily D’OXYVA applications and shared that he saved money by using D’OXYVA and beginning to wean off of other medications. 

#1 Check Your Feet Carefully Every Day for Diabetes Induced Changes
Diabetic patients must check their feet carefully every day to look for suspicious areas of skin breakdown, color changes, callus formation and skin infections. Areas that are especially vulnerable to skin breakdown include the big toe, the heel and the areas between the toes. Diabetics are extremely vulnerable to damage to the microcirculation (smallest blood vessels) of the feet. The application of transdermal vasodilators such as D’OXYVA can increase peripheral oxygenation to avoid further nerve damage and other diabetes induced changes while improving wound healing and avoiding amputations.
#2 Wear Properly Fitting Shoes
Shoes that are too tight can impair circulation. Care should be taken to ensure a proper fit so that circulation is adequate and there is no inordinate friction or rubbing.
#3 Keep Your Feet Dry, Especially in the Winter
Excessive moisture caused by sweating of the feet can lead to increased bacteria growth, which can cause infections. Socks should be changed regularly in the winter especially, if they become wet.
#4 Use Moisturizer on Your Feet After Bathing
The nerve damage and vascular changes to the feet caused by diabetes lead to dysfunction of the moisturizing glands and result in increased dryness, which can cause further skin breakdown. Applying a moisturizer to the feet (but not between the toes) after bathing can restore lost moisture and reduce dryness.

HOW D’OXYVA CAN HELP?

D’OXYVA is the only fully noninvasive, completely painless over-the-skin microcirculatory and nerve stimulant solution that has been validated to significantly improve microcirculation.

The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.

Experience Significant Pain Relief Now!

        BUY D’OXYVA

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10 Common Misconceptions About Pain Management

pain reliever

Chronic pain is a worldwide phenomenon that requires different treatment approaches for different patients. A number of common misconceptions about proper pain management exist, and these can affect the efficacy of a pain management program. Read on to learn about the case of Amy B., who required a specialized pain management approach to control her chronic pain.

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Amy B. was a 67-year-old female patient with severe pain from multiple fractures and osteoarthritis. She was originally prescribed Tylenol with codeine, which did not control her pain. After the addition of the non-invasive deoxyhemoglobin vasodilator D’OXYVA[1], Amy was completely pain free within 6 weeks.

Misconception #1

All Patients Complain About Their Pain Levels to Obtain Pain Medications
Although some patients who seek pain medications to feed drug addictions do “over complain” about their pain levels, studies have consistently shown that the vast majority of legitimate pain management patients accurately describe their pain levels using a pain scale that ranges from 1 to 10.
Misconception #2

Narcotic Pain Medications Are Always the Best Chronic Pain Treatments
Many other modalities[2] can be attempted before using narcotic pain medications. These alternatives include physical therapy, massage therapy, biofeedback, stretching and exercise. In addition researchers have found that the application of the non-invasive deoxyhemoglobin vasodilator D’OXYVA significantly decreases pain, especially in patients with diabetic neuropathy.
Misconception #3

All Pain Management Patients Should Start on NSAIDs
Depending on the patient’s pain level, other medications such as opioids may be the appropriate first choice for adequate pain control.
Misconception #4

All Pain Management Patients Are Drug Addicts Who Are Seeking Drugs
Legitimate pain management patients with conditions such as severe arthritis, gout, spinal stenosis, diabetic neuropathy, or diabetic foot ulcers are not drug addicts even though they require daily pain medications. Other types of patients with conditions such as obsessive compulsive disorder or actual drug addictions may seek to divert pain medications to feed their addictions.
Misconception #5

Treatment with Opioid Pain Medications Always Completely Eliminates a Patient’s Pain
The goal of pain management is to reduce a patient’s pain level using the lowest dose of opioids possible. This does not always result in complete pain relief. Other modalities such as the application of D’OXYVA can be used to help control chronic pain.
Misconception #6

If One Type of Opioid Does Not Correct Chronic Pain, No Opioids Will Ever Control Chronic Pain
This is inaccurate. For example, if codeine does not adequately control a patient’s pain, a different class of opioids such as hydrocodone may be required for pain relief.
Misconception #7

Patients Should Not Have Control over Their Opioid Pain Medications
Pain management patients should be in control of their own pain medications because they are in the best position to determine their actual pain control level and to know whether their pain medications are working.
Misconception #8

Non-Invasive Pain Control Applications Such as D’OXYVA Have No Scientific Basis
Multiple studies have shown the efficacy of non-invasive applications such as D’OXYVA in controlling acute and chronic pain.
Misconception #9

Chronic Pain Patients with Peptic Ulcer Disease Can Use NSAIDs Safely
NSAIDs should be used with care because they can exacerbate conditions like peptic ulcers or gastritis.
Misconception #10

NSAIDs Used Topically for Chronic Pain Cause GI Problems
There is no evidence that topical NSAIDs cause this side effect.
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HOW D’OXYVA CAN HELP?

D’OXYVA is the only fully noninvasive, completely painless over-the-skin microcirculatory and nerve stimulant solution that has been validated to significantly improve microcirculation.

The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.

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The Next Big Thing in Diabetic Foot Pain Management

foot pain

Diabetes Mellitus Type 2 is a severe, chronic medical condition that affects approximately 23.1 million[1] patients in the United States (9.4% of the US population). In addition, each year, 800,000 people will be newly diagnosed with diabetes. Diabetes can lead to the development of blindness, strokes, end stage renal disease, heart disease and diabetic neuropathy. Read on to learn about the case of Leo, who suffered from severe diabetic peripheral neuropathy.

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Case of a Patient with Diabetic Foot Pain

Leo was a 64 year old male patient with a long history of diabetes type 2.

Leo had a history of smoking cigarettes for the past 25 years.

He also had a history of hypertension, which was well controlled with lisinopril.

In addition, Leo had elevated cholesterol levels controlled with the use of a statin.

He denied any history of anxiety or depression.

Leo complained of a burning, very painful feeling in his hands and feet, which kept him up at night.

He also had some problems maintaining his balance and noted attacks of burning pain on the soles of his feet, often when driving his car.

On physical examination, Leo exhibited ataxia, vertigo and decreased vibratory sensations over his lower extremities.

His reflexes and the pedal pulses of the lower extremities were both intact bilaterally.

Leo’s labs revealed a fasting blood sugar of 146 and a hemoglobin A1C level of 7.8% (normal is less than 5.7%).[2]

Leo’s B12, T3, T4 and TSH levels were all within normal levels.

He also had a BMI of 40%.

After application of the over-the-skin deoxyhemoglobin peripheral vasodilator, D’OXYVA, [3] over a 6 week period, all of Leo’s symptoms of diabetic neuropathy, including the burning, itching and painful feeling in his hands and feet stopped completely.

How is the Microcirculation Affected by Diabetes?

The microcirculation consists of the smallest blood vessels in the body, including the arterioles, venules and capillaries.

Consistently elevated blood sugar levels are considered to be the most important risk factor in the development of painful diabetic neuropathy.

Diabetic neuropathy usually begins to develop at the base of the toes and then subsequently affects the higher parts of the lower extremities.

The most common symptoms of diabetic neuropathy include numbness, a feeling of burning, tingling and “pins and needles.”  

Other symptoms of diabetic neuropathy are muscular weakness of the lower extremities, poor coordination and ataxia.

Once the numbness increases, there can then be a loss of pain perception, which can lead to the development of foot ulcers, infections and even eventual amputations.  

How Does D’OXYVA Help Decrease Diabetic Foot Pain?

D’OXYVA is a non-invasive vasodilation applicator, which is placed over the thumb and delivers a vapor of pharmaceutical grade CO2 and water through the skin of the thumb and into the blood stream.

This CO2 is then transported by the microcirculation to the peripheral arterioles, which causes them to dilate, providing increased oxygen to the peripheral tissues.

This increased oxygenation then leads to a decrease of pain resulting from diabetic neuropathy.

Conclusion

Diabetic neuropathy can cause debilitating pain, which can affect sleep patterns and quality of life. Current treatments include the use of tricyclic antidepressants, antiarrhythmics, antiepileptics, opioids and topical creams. The application of the non-invasive, non-painful over-the-skin deoxyhemoglobin vasodilator, D’OXYVA, has been widely reported to significantly lower the levels of pain and discomfort caused by this common complication of diabetes.

HOW D’OXYVA CAN HELP?

D’OXYVA is the only fully noninvasive, completely painless over-the-skin microcirculatory solution that has been validated to significantly improve microcirculation.

The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.

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Prevention of Amputations in Diabetics

Prevention of Amputations in Diabetics

A major risk of having diabetes is the possibility of requiring an amputation. Most frequently, amputations due to diabetes first involve the great toe with worsening gangrene, which leads to amputation of the foot, amputation of the leg below the knee, and then amputation of the leg above the knee. The following is a case study of Douglas, who was a diabetic patient who required an amputation of his lower leg beneath the knee in order to survive.

Case of a Sixty-Three-Year-Old Man with an Amputation of the Left Lower Leg from Uncontrolled Diabetes

Douglas was a sixty-three-year-old patient with a past medical history that was significant for Type 2 diabetes mellitus and high blood pressure with an inability to walk more than two blocks without shortness of breath. Because his blood sugars were continually out of control even on insulin, Douglas developed damage to the nerves in his feet (peripheral neuropathy). This led to his inability to feel an ulcer forming on the tip of his left great toe. In addition, since his diabetes led to damage to the microcirculation (smallest blood vessels) in his feet, his ability to rapidly improve  from the ulcer was significantly delayed. Within forty-five days of the first occurrence of the blister, it became infected, which led to gangrene and sepsis and admission into the intensive care unit. The gangrene kept spreading, requiring first the amputation of his left great toe, then the amputation of his left foot, and finally the amputation of his entire left leg below the left knee. This case demonstrates how the extreme and potentially deadly risk of leg amputations in diabetics can be reduced through early diagnosis of the problem and aggressive preventative care, including the use of D’OXYVA[1].

D’OXYVA is a peripheral and noninvasive deoxyhemoglobin vasodilator that dilates the microcirculation (D’OXYVA delivers pharmaceutical grade CO2 and water vapor transdermally (through the skin), dilating the smallest veins, arteries, and capillaries while increasing peripheral blood flow to the lower extremities. D’OXYVA is a pain reliever that is given for fast pain relief treatments, which are known to reduce pain and chronic conditions.

Risk Factors for Amputations in Diabetics

In a study published in the Journal of Developing Countries in 2008, it was found that, of 146 diabetic patients studied who had amputations of the foot, 74% had had diabetes for two to forty years.

In addition, forty-seven percent of the patients who were studied had ischemia (reduced blood flow), and forty-four percent had neuropathy (reduced nerve function) of the foot involved.[2]

How to Decrease the Risk of an Amputation Due to Diabetes?

Steps you can take to decrease the risk of an amputation if you are diabetic [3] include:

  • Keep your blood sugars well under control to decrease the risk of peripheral neuropathy and peripheral vascular disease.
  • Check blood sugars as directed by your physician.
  • Check your feet and toes for changes in temperature or feeling every day.
  • Examine your feet daily for cracks, blisters, cuts, redness, white areas, thick calluses, and different changes in color.
  • Stop smoking.
  • Stay on a Diabetic diet.
  • Increase daily exercise levels.
  • Continue to take all prescribed medications.

HOW D’OXYVA CAN HELP?

In an ongoing multi-year, multi-country, multi-center, randomized clinical trial on patients with diabetic foot ulcers, D’OXYVA has demonstrated speeding up diabetic wound improve and ultimately wound closure to an average of 5 weeks**.

In addition, D’OXYVA eliminated pain and improved quality of life such as sleep, appetite and mood in just a week in 100% of subjects. No adverse events of any kind were reported during, and years after the studies.

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The Many Options for Non-Invasive Treatments in Pain Management You Didn’t Know

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Many patients suffer from chronic pain, with little or no relief from opioids, physical therapy or even surgical treatments. For example, Ritchie was an athletic 35-year-old man who had been diagnosed with a condition called Osgood-Schlatter’s[1] Disease at the age of 15. This condition, which is a result of rapid lower extremity bone growth in adolescents, resulted in Ritchie’s suffering with bilateral knee pain and swelling below his kneecaps. At the age of 17, Ritchie underwent arthroscopic surgery on his right knee to remove damaged cartilage. Despite this treatment, he remained in chronic pain that was unrelieved by pain medication, anti-inflammatories or physical therapy. After his physician prescribed a 7-week course of daily D’OXYVA[2] treatment, Ritchie became pain free and was able to resume all of his former sports activities, including tennis and golf.

How Common is Chronic Pain?

According to the National Center for Complementary and Integrative Health[3]chronic pain (pain lasting more than 3 months) is extremely common, affecting more than 25 million American adults every day.

In addition, at least 40 million American adults suffer from non-daily but severe chronic pain.

Patients with severe chronic pain were found to generally suffer from more chronic health problems and more disability than patients with less severe pain.

What Causes Chronic Pain?

Chronic pain can result from an injury or from a disease or condition, such as one of the following:

  • Osteoarthritis
  • Rheumatoid Arthritis
  • Fibromyalgia
  • Migraine Headaches
  • Cancer
  • Diabetic Neuropathy
  • Carpal Tunnel Syndrome
  • Post-Surgical Pain

 

Non-Invasive Treatment Options for Chronic Pain

The following have been found to be useful in the treatment of chronic pain:

  • Acupuncture
  • Massage Therapy
  • Comfrey
  • Mindfulness-based Stress Reduction
  • Progressive Relaxation
  • Spinal Manipulation
  • Yoga
  • Herbal Products, such as cayenne pepper, lavender essential oil, white willow bark and devil’s claw
  • Electromagnetic Therapy
  • Biofeedback
  • Hypnotherapy
  • Meditation
  • Tai Chi

 

The Use of D’OXYVA in the Treatment of Chronic Pain

Microcirculation refers to the blood flow in the smallest blood vessels of the body, which are the venules (smallest veins) and the capillaries (connect venules and arterioles). When the microcirculation is compromised or blocked and blood flow to the nerves is reduced, chronic pain can ensue.

D’OXYVA is a commercially available non-invasive deoxyhemoglobin vasodilator that when applied to the thumb delivers a high level of pharmaceutical grade carbon dioxide (CO2) and water vapor.

The CO2 diffuses through the skin and is delivered through the blood stream, traveling to the smallest blood vessels of the body, where it has a vasodilating effect[4] and acts as a nerve stimulant that helps relieve neurogenic pain.

Diabetic patients with uncontrolled blood sugar have reported neuropathy pain relief within minutes of administration of the D’OXYVA device.

In summary, D’OXYVA is an excellent pain reliever for many different types of chronic pain.

HOW D’OXYVA CAN HELP?

D’OXYVA® (deoxyhemoglobin vasodilator) has achieved over 90%* elimination of all sorts of chronic pain in 100% of subjects either the same day or in a few days, such as from a very high 8 to a very low 1 on the Visual Analog Scale (VAS).

Pain-free life is here. Beyond major clinical outcomes for mild to extremely severe conditions, even when strong opioid-based painkillers were ineffective, new and long-term users of D’OXYVA reported relief of persistent long-term chronic pain in 2 – 7 days associated with: Neuropathy, fibromyalgia, chemo-, and radiation therapy, chronic wounds, arthritis, osteoporosis, migraine headaches, and lower back pain.

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Defects in Microcirculation and the Effect on Wound Healing: New Non-Invasive Treatments

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

The effects of defects in and poor functioning of the microcirculation on wound healing, especially in diabetic patients, can be devastating and life changing. As one particular example, Joseph L was a 63-year-old White male with a 24-year history of diabetes mellitus, hypertension, elevated cholesterol and arthritis. Joseph had been taking insulin for the past 12 years but his blood sugar levels were still poorly controlled.

On physical exam, Joseph had several very large, oozing and foul smelling deep ulcers located on the dorsum (top) of the left foot. After 8 weeks of intensive therapy utilizing the non-invasive D’OXYVA transdermal deoxyhemoglobin vasodilator, Joseph’s ulcers healed entirely and he avoided amputation of his left foot. Read on to learn more about this new non-invasive wound treatment that helps in wound healing.

 

What is the microcirculation?

The microcirculation refers to the smallest blood vessels in the body that supply oxygen to the tissues and remove waste products. This includes the arterioles, the venules and the capillaries. When the vessels of the microcirculation become damaged, it leads to decreased blood flow with lower oxygen blood levels and resultant damage to the skin resulting in a wound or ulcer.

Risk Factors for the Creation of Chronic Wounds

Patients with the following risk factors are at greater risk for non-healing wounds or ulcers (ulcers are the most common type of chronic wounds):

  • A history of decreased blood flow to a specific area (ischemia)
  • A history of uncontrolled diabetes (which leads to poor circulation, nerve damage and breakage of the skin)
  • A history of uncontrolled hypertension (high blood pressure)
  • A history of high cholesterol and atherosclerosis (cholesterol plaques in the arteries)
  • A history of blood clots (thrombosis)

 

Diabetic Foot Ulcers

Diabetic foot ulcers are a common complication of uncontrolled diabetes mellitus.1 Chronically elevated blood sugar levels damage the microcirculation of the lower extremities, which leads to ischemia and neuropathy (damage to the nerves). Diabetic patients often lose feeling in the feet and so are not aware of friction and pressure, which leads to breaks in the skin. This subsequently leads to open wounds that often do not heal over a 30 day period. These wounds can then become infected, leading to gangrene and eventual amputation.

 

An Example of a New Non-Invasive Treatment to Enhance Wound Healing

D’OXYVA is a non-invasive transdermal deoxyhemoglobin vasodilator that delivers FDA-approved ultra-purified CO2 molecules which diffuse through the skin leading to increased skin perfusion. In studies of the treatment of diabetic foot ulcers with D’OXYVA, increased diabetic wound healing was observed with wound closure often observed within 5 weeks.

 

Conclusion

Chronic conditions like uncontrolled diabetes and hypertension can cause damage to the microcirculation, which leads to delayed wound healing. New treatment methods like D’OXYVA deliver transdermal CO2-enhanced oxygen and nutrients to wound areas through the microcirculation. This speeds up wound healing and wound closure and helps avoid devastating complications such as amputations.

HOW D’OXYVA CAN HELP?

In an ongoing multi-year, multi-country, multi-center, randomized clinical trial on patients with diabetic foot ulcers, D’OXYVA has demonstrated speeding up diabetic wound healing and ultimately wound closure to an average of 5 weeks**.

In addition, D’OXYVA eliminated pain and improved quality of life such as sleep, appetite and mood in just a week in 100% of subjects. No adverse events of any kind were reported during, and years after the studies.

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A Success Story: Enjoying the stage again after years of chronic pain

chronic pain success story

Rachel shares how her healthcare professionals, along with the use of D’OXYVA, have helped her every step of the way.

My story started 2 years ago when I severely injured my ankle. At that time, I was working hard preparing for a dance presentation. I am a professional ballet dancer; my injury happened after a grand jeté, when I landed badly on my right foot. I needed to undergo surgery and rehab.

It was so painful that I had a hard time sleeping. Luckily, I got some pain meds so I could fall asleep. The nights were rough. I would wake up every two hours to call the nurses and ask for more medicine.

According to the doctors, this fracture could leave me limping for life. When I heard those words, my world just fell apart. I didn’t know how to accept my situation. I wouldn’t be able to dance again? I wouldn’t be able to walk again? I started to view life differently; I was hopeless.

I had to undergo months of rehab and physical therapy. Luckily, I had my friends and family to support me all the way. I slowly noticed I was feeling better; I could slowly stand up and take a few steps.

A few weeks before Christmas, due to my eagerness to recover so I could dance again, I once again aggravated my ankle after forcing it. The pain was excruciating; it felt like the first time I fractured it. That time I thought, “I’m done. I’m giving up; I will never really be able to dance again.” I had to undergo surgery and rehab for the second time, but this time, I didn’t feel like doing it; I thought it was useless, much more so after the doctor told me that the chances I could dance again were small.

One month later, I met Janina, my co-ballet dancer, at the rehab center undergoing the same physical therapy as I was. She told me she had just fractured her ankle about 4 weeks earlier; I was amazed at how fast she seemed to be recovering. I couldn’t help but ask what she had been doing or what medications she had been taking.

She then pulled a device from her bag and said, “This is D’OXYVA. This helped me with my recovery really well.” I was intrigued. Janina told me that her mother, who is diabetic, had been using D’OXYVA to manage her neuropathy and her diabetic wound, so she thought it might help her, too. Indeed, it helped her recover quickly, and she barely felt any pain from her injured ankle.

When I arrived home, I turned on my computer and did my research on D’OXYVA. Their customer support was very helpful with all the questions I had.

After almost 4 weeks of twice daily D’OXYVA therapy with the help of my orthopedic doctor and therapist, I was walking; after 5 weeks, the pain was almost gone. Now, it’s been almost 8 weeks, my D’OXYVA therapy has been reduced to 4 times a week, and I’m back at the rehearsal studio. It was an unexpected turn of events. I went from hopeless to hopeful!

I am still continuing my D’OXYVA therapy at least 3 times a week and working my way to becoming fully recovered. I’d like to thank Janina for introducing me to D’OXYVA. It gave me hope and positive vibes during my recovery stage. As for the D’OXYVA support staff, my orthopedic doctor, and my physical therapist, I couldn’t ask for a more professional, caring, and extremely helpful group. They are just plain AMAZING, all of them!

HOW D’OXYVA CAN HELP?

D’OXYVA improves blood oxygenation. Oxygen is one of the body’s natural healers. If you have ever taken deep breaths to help reduce your stress or pain, you know that increasing oxygen flow throughout your body can help with healing and minimizing pain.

In various clinical studies, D’OXYVA® (deoxyhemoglobin vasodilator) has achieved over 90%* elimination of all sorts of chronic pain in 100% of subjects either the same day or in a few days, such as from a very high 8 to a very low 1 on the Visual Analog Scale (VAS).