D'OXYVA® Advanced Circulation | Applicator

The industry-leading solution in your hand

happy doxyva family sm

D'OXYVA® Advanced Circulation | Applicator

The industry-leading solution in your hand

(22 customer reviews)


Happening from December 1, 2020 8AM PST to December 4, 2020 8PM PST!

*use code: CYBERWEEK35
*no minimum purchase required

Recommended by top physicians, D’OXYVA®‘s advanced circulation health set significantly improves circulation of blood flow, microcirculation, beneficial nerve functions with each 5-minute gentle D’OXYVA application on your skin with an exceptional safety & efficacy profile.

D’OXYVA’s elegant circulation health solution was designed for everyone who wants to live life to the fullest, pain free & healthy. There’s nothing like D’OXYVA!

Select your applicator color from the below menu & make sure you add cartridge supplies in your cart to reach your health goals as needed.




Significant results in 4-8 weeks*

D'OXYVA Once a day,
5 Days/Week



Your Fast & Pleasant Journey

To Total Health Starts Here

No Matter How Severe

Your Condition Is

Fast, Painless, Noninvasive

D’OXYVA®‘s handheld, non-electrical applicator gently delivers its proprietary supersaturated vapor solution on the surface of the skin in a few minutes to provide long-lasting major benefits. The results of quality pivotal human studies with D’OXYVA strongly suggest that the exceptional benefits are the result of significantly improved circulation, vascular health, and so-called hypoxia inducible factors.

Each single 5-minute application on a thumb or near an affected body part provides over 4 hours of circulatory, neurological and other critical benefits for speeding up chronic pain relief, getting rid of the appearance of diabetic foot wounds, spider and varicose veins, besides other major outcomes to an average of 4-8 weeks, according to several human studies*.

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easy to use daily

How To Use D'OXYVA?

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Painless Anywhere on Skin

D’OXYVA is a fully non-invasive, non-irritating, non-opioid, and completely painless, gentle over-the-skin application.

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

5-Minute Daily Application

D’OXYVA’s pioneering biotechnology provides a simple, effective route of administration in just 5 minutes each day.

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Home & Professional Use

The D’OXYVA applicator and single-use cartridges can be purchased here online, without the need for a prescription.

D’OXYVA® (deoxyhemoglobin vasodilator) is the pioneering non-invasive biotech solution created by the health science experts at Circularity — proven to deliver a wealth of health, athletic, and cosmetic benefits in a single painless, convenient, and affordable care.

D’OXYVA provides accelerated and comprehensive injury recovery, athletic performance, chronic wound care — plus infection protection — in a painless, affordable non-prescription solution available in a clinical setting, or in the comfort and privacy of your own home or virtually anywhere.

easy to use daily

How D'OXYVA Works?

For example, D’OXYVA® naturally delivers remarkable and fast pain management results without the use of opioids. In high-quality studies, it has demonstrated noticeable efficacy in the reduction and elimination of chronic pain — achieving over 90% elimination of all varieties of chronic pain in nearly all enrolled subjects the same day or in a few days.

D’OXYVA® (deoxyhemoglobin vasodilator) is a handheld applicator that’s the first biotech solution of its kind, underpinned by widely established, groundbreaking, Nobel Prize–winning science.

It’s been studied to significantly improve macro-, and micro-circulation of blood flow and certain nerve activities in the body, which is widely reported to boost fitness and form an effective noninvasive, pain-free solution for several widespread conditions.


The D’OXYVA® applicator’s rugged and durable design weighs less than a pound and requires an ounce of clean drinking water combined with Circularity’s disposable and recyclable cartridges. No electricity, costly equipment or special training is necessary to get started on a new you.

Circularity’s powerful noninvasive and all natural skin delivery Regenerative Solution (D’OXYVA) is the only real regenerative product validated on people and identified as a Non-Significant Risk device for skin delivery showing significant lasting improvements in oxygen-rich blood flow in the microcirculation as measured in trials with U.S. FDA-cleared noninvasive Skin Perfusion Pressure (SPP) diagnostics.

Additional information

Weight1 lbs
Dimensions15 × 5 × 5 in

22 reviews for D’OXYVA® Advanced Circulation | Applicator

  1. Dyke (store manager)

    My work requires me to stand for long hours. It’s not a shocker i have varicose veins. But thanks to D’OXYVA, they aren’t as obvious as they looked a few months back! This is definitely an innovation!

  2. Freddy Simons (store manager)

    D’OXYVA is good for headache, you should start using it. A combined routine, including proper exercise, diet & D’OXYVA, I have seen positive effect on my body. It elevates flow of blood to brain and enhances one’s memory. It also keeps you mentally strong.

  3. Princess Mariott (store manager)

    Loving my D’OXYVA! I just had a major surgery and was introduced to D’OXYVA, they said it will make my improve faster so I can go back to work right away. I feel a whole lot healthier ever since I tried the solution. The doctor said normally my wound will improve in 6 months, but in only almost 4 months my wounds are closed and I’m back on my feet with almost no pain! Been having the solution once a day for the past 3 months!

  4. Terence King (store manager)

    suffered from a burn and I had difficulty walking. Got to try D’OXYVA and it definitely hastened the improve process! The next goal is to get rid of the scar!

  5. E. Mason (store manager)

    I did not expect these results at all but I am happy I did give this product a shot. D’Oxyva makes me sleep better at night and increased my sex drive. I can accomplish more things during the day with my energy up. Great product.

  6. Rejean (store manager)

    Always wanted to get rid of my varicose veins without undergoing surgery. Luckily for me, I got to try D’OXYVA, applied the solution onto my leg and after some weeks, I definitely saw some improvements!

  7. Rob Santiago (store manager)

    My bestfriend’s mom has diabetes and she was looking for an alternative to treating her wounds which are very slow to heal. She was referred to D’OXYVA and has been on it ever since. She’s been saying she’s feeling waaaay better than she ever did! It’s not only her diabetic foot that’s been better, she can now have long walks for exercise which she couldn’t do before. I’m so happy for her and my bestfriend.

  8. Haley Stewart (store manager)

    I had painful varicose veins and more on my left leg, I tried alot of creams to no effect.
    So I researched for more effective creams and got lucky to find doxyva solution. I was kind of skeptical at first but i am so happy with the results. Thanks!

  9. James Atitio (store manager)

    I have been a D’OXYVA user since 2015 and still using it now. It helps me with my stamina and endurance. I love that I was able to avail of their Going Global sale!

  10. Kimberly Banzon (store manager)

    Suffered from a minor burn two months ago and was advised by my doctor to use d’oxyva to improve fast and it worked! Great product!

  11. Moira Gatchallian (store manager)

    Happy with my D’OXYVA. Using it to improve my stamina for running and exercise. I’ve really improved within just months of using it!

  12. Emily Bright (store manager)

    Was introduced to D’OXYVA from a health forum online that it is effective to improve the appearance of spider veins, I tried it and been using it for 2 months now, so far the appearance of my spider veins significantly improved even without surgery!

  13. Joshua M. (store manager)

    I started D’OXYVA 4 weeks ago. It works very well. My high pressure is reducing without taking any type of medicines. I was feeling very good after using D’oxyva. Easy of order which saves time.

  14. Jorge Manuel Lopez Jr (store manager)

    I have been diagnosed to be diabetic when I was 43 years old and was told by my doctors to modify my lifestyle and diet. Sure I did, and my friend who’s also diabetic referred me to this microcirculation therapy called DOXYVA. I did the free trial for a month and noticed little changes in my day to day life. Decided to try it for one more month, and that’s when I noticed very noticeable changes. My sugar levels are not that high anymore and my o2 saturation has improved (monitored through an oximeter). I’m so happy!!!

  15. Eric Clarkson (store manager)

    since my DM type II diagnosis, I’ve been looking for alternative ways of controlling my sugar and blood pressure. So I was curious when I came across D’OXYVA. I decided to try it, and the results have been nothing short of great! My sugar levels and blood pressure are maintained, I feel less fatigued, and I generally feel so great!

  16. Zara M (store manager)

    I have seen significant results with DOxyva for my skin since i started, im on my 4th month and I highly recommend it to my friends.

  17. aggoddard (store manager)

    however , i think the design should be modified to have the on/off button operate differently . when screwing the cartridge cup on I tend to grab the device in the middle and this inadvertently push the button to the on position . This makes the cartridge work prematurely and I don’t get the full 5 minutes of performance . The on/off button should work in opposite to the way they work now . I have noticed that when I test oxygen level with a finger oximeter the value is usually about 4 points higher after treatment . Don’t know how long this lasts , but does indicate that I am upping the level upon treatment

  18. Stephen Goddard (store manager)

    it is too soon to tell if this device is providing the outcome i am looking for re diabetic peripheral polyneuropathy .

  19. K. Jackson (store manager)

    I read online about the benefits of using D’OXYVA so I decided to try their 30-day trial. Just two weeks into using it, I notice a boost in my energy. I now can do other things which I could not do before. Great product!

  20. M Santos (store manager)

    Was diagnosed with RA a few months ago. Have been suffering from the pain and it was unbearable! I met this person who also had RA and was using D’OXYVA. I tried for myself and it really is fortunate that I am relieved of the pain

  21. J. Marshall (store manager)

    i am using DOXYVA for my arthritis and it is doing the work for me. Pain is somehow manageable now. Glad I stumbled into this product. It’s a life saver!

  22. R.Bernards (store manager)

    This device is amazing! I can’t help but be grateful how I am feeling better every morning and sleeping very well now. Thank you D’Oxyva! Your customer service is also great!

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D’OXYVA uses simple, ultra-purified gaseous molecules - administering them via its fully non-invasive skin delivery system.
D’OXYVA‘s over-the-skin route of administration has demonstrated a safer, more effective alternative route to inhalation — a routine delivery method in hospitals.
D’OXYVA’s platform solution uses vaporized ultra-purified carbon dioxide that acts as a catalyst for the body to help improve its functions and heal itself.
Purified carbon dioxide is a non-toxic molecule and can be sold by Circularity and online without the need for a prescription. Our products are manufactured in compliance with the highest standards.

Doesn’t Your Health Deserve D’OXYVA®?

        BUY D’OXYVA


User Reviews

Jesse Golden
Jesse Golden
CEO of The Golden Secrets
Read More
"I was amazed at how the swelling and stiffness in my joints went away and I had more energy! The best part is they market this product also for its beauty benefits. It can help with acne, wrinkles, spider veins, stretch marks and cellulite! Check out Circularity!
Scot Clark
Scot Clark
Read More
"I'm a hair dresser for 40 years and still working behind the chair, my legs suffered some consequences, using D’Oxyva certainly has helped with all the spider veins and I certainly have no discomfort when standing all day. Thanks again D’Oxyva for a true revolutionary product.
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"This gadget is amazing! It really helped reduce my back pain and my Covid-19 symptoms in a few days. Absolutely love it!"
Kate H.
Kate H.
Read More
“I have been using the D’Oxyva for years. The varicose veins on my legs don't show as much or at all. I don’t have to stretch in the morning, it gives me more energy during the day. Love it!”
Read More
"Love my D'OXYVA. Everyone needs this to stay fit and healthy and above all, stay in shape with a healthy weight. It only takes a few minutes a day. Must try!"


Discover the Science Behind D'OXYVA

doxyva applicator cross section

D’OXYVA® (deoxyhemoglobin vasodilator) is the only fully non-invasive, non-irritating, non-opioid, and completely painless, skin delivery (over-the-skin) nerve stimulant and microcirculatory solution.

With over seven years of industry-leading research results, D’OXYVA® demonstrated that it does not break the skin’s barrier while it provides outsized quality of life and outcomes quickly and affordably.

In short, based on current leading neurology, immunology, microvascular, and cellular oxygenation science, D’OXYVA® is leading the field by:

✓ Significantly lowering the risk of diabetes and cardiovascular complications.

✓ Providing complete significant improvement of difficult wounds together with major pain relief and improved quality of life.

D’OXYVA®‘s gentle vapor solution with purified CO2 readily dissolves in a molecular form in the skin, acting as a catalyst to improve skin perfusion pressure and optimize nerve functions and microcirculation.

D’OXYVA® delivers fast solution to the areas you need it most. It’s also easy-to-use virtually anywhere — even from the comfort and privacy of your own home.

How To Start?

Follow the Standard Application Guide — Or, Get Your Personalized Plan

Significant results in 4-8 weeks*

D'OXYVA Once a day, 5 Days/Week

D'OXYVA | Cardiovascular, Diabetes Care, Pain Reliever in CA.

Over two dozen studies demonstrated sterling results at clinics and at home with zero adverse events. D’OXYVA® (deoxyhemoglobin vasodilator) has recorded significant results, delivering major outcomes for well over 90% of users.

Average results rounded for display, based on number of enrolled subjects in each study with D’OXYVA® and user feedback.

Read D’OXYVA® Clinical Evidence

Ask your doctor before taking D’OXYVA®.

Read D’OXYVA® Regulatory Statements

We will refund your entire D’OXYVA® purchase price if you do not achieve any measurable improvements (proof of purchase required, improvements of blood flow (perfusion index) measured from absolute baseline without taking D’OXYVA®).

Read Circularity’s Return Policy

most frequent questions and answers


Correct. That’s why D’OXYVA’s gentle process demonstrated that it does NOT significantly increase the CO2 content in the blood or tissue and instead reduces the CO2 content per partial pressure of oxygen (O2). This just means D’OXYVA oxygenates the blood and tissue due to inducing the beneficial Bohr effect. In addition, CO2 is a so-called ‘gasotransmitter’ that signals the autonomic nervous system in the brain to launch protective mechanisms that tend to move a host of critical functions into balance (homeostasis).

Search the terms we use on this site on the internet to learn more and measure your own results at home or with your doctor with a pulse oximeter for one example. Then watch your blood oxygen (SpO2) and perfusion index (peripheral blood flow) rise quickly in just a half an hour and hour that stays elevated for several hours after a single 5-minute D’OXYVA (single 16g cartridge)! Measure results with your blood pressure and blood glucose meter. For example, take it before your workout to boost energy and after for rapid recovery. Take it to restore healthy blood flow for your foot wounds or back pain or headaches. Reduce the risks of major infections, chronic illnesses and skin damage.

Simply by reducing the need to spend on expensive modalities that just don’t work at the underlying problem, they only act as an expensive bandaid. However, with the help of D’OXYVA your body gets to the bottom of the problem and starts regulating critical functions to restore order and even generate new and highly beneficial resources such as vessel structure growth, tissue repair, cell production and other hormonal and neural functions. Take D’OXYVA together with your beloved supplements, vitamins and even necessary medications and treatments to boost their efficacy and likely reduce any negative effects you may be experiencing from some of them.

Reduce unwanted doctor visits, recommended and ranked top by experts!