CLINICAL EVIDENCE

Circularity Healthcare has been assembling a world-class scientific advisory board (partial list) that includes domestic and international medical thought-leaders in the field of diabetic relief, amputation prevention, micro-vascular physiology, neurology, endocrinology, vascular surgery, cardiovascular physiology, exercise science and others.

D’OXYVA^® has demonstrated an exceptional efficacy and safety profile in quality human pivotal clinical studies including placebo-controlled double-blind, randomized trials and has been investigated at prestigious institutions around the world such as Penn State University, Florida State University, Valley Presbyterian Hospital, Hospital Kuala Lumpur, Airlangga University, Chulalongkorn University, University of Szeged, National Taipei University and others. Currently, its diabetic foot ulcer closure human pivotal trials are expanding to over a dozen top U.S. universities conducted by influential medical experts who are regularly called upon to testify in front of the U.S. Food and Drug Administration (FDA).

Improved oxygen-rich microcirculatory tissue perfusion is widely reported in published research to improve physiological processes that lead to significant health benefits and outcomes. These include, but are not limited to chronic, burn, trauma wound and tissue improvement and repair, boosting athletic performance, stamina, sleep quality, fading the appearance of spider and varicose veins, while aiding in skin health, and much more.

D’OXYVA has recorded instant, outsized, and sustained improvements of the autonomic nervous system (ANS) in the brain, enhanced tissue perfusion and blood circulation in macro-, and microcirculation, chronic wound closure and balanced blood pressure in controlled human studies.

The D’OXYVA mechanical applicator is a handheld, non-invasive skin infusion technology. Therefore, it is a non-significant risk (NSR) device, according to FDA guidelines.

Please contact us if you would like participate as a subject or health professional in Circularity’s clinical study program called the Center of Excellence (COE) program.