D’OXYVA’s platform solution acting as a catalyst for the body to heal and improve itself is vaporized ultra-purified medical and pharmaceutical carbon dioxide. Purified CO2 is a non-toxic pharmaceutical molecule cleared by the U.S. FDA, the European Medicines Agency, and nearly all drug regulatory agencies worldwide registered in their respective pharmacopeias, and can be sold by Circularity over the counter (OTC) and online without the need for a prescription.

CO2 is a non-toxic substance according to the FDA and delivering it via transdermal means (over-the-skin) by D’OXYVA has demonstrated a much better and safer alternative route to inhalation, a routine delivery method in hospitals for anesthesia.


D’OXYVA uses medical or pharmaceutical carbon dioxide and delivers it via its fully non-invasive transdermal delivery system.


Our products are manufactured in compliance with the highest medical device standards (e.g., EN ISO13485:2012).




Take it daily—in a few weeks significantly reduce the risks of:

Chronic diabetic & vascular, burn, trauma wounds


Type 1 & 2 diabetes


Chronic venus insufficiency, varicose veins


High blood pressure, stroke, hypertension

D’OXYVA (deoxyhemoglobin vasodilator) is the only fully non-invasive, non-irritating, non-opioid, and completely painless, transdermal (over-the-skin) microcirculatory solution.


With over five years of industry-leading clinical research results, D’OXYVA demonstrated that it does not break the skin’s barrier while it provides outsized quality of life and clinical outcomes quickly and affordably.


In short, based on current leading neurology, immunology, microvascular, and cellular oxygenation science, D’OXYVA is leading the field by:


Significantly lowering the risk of diabetes and cardiovascular complications


Providing complete healing of difficult wounds together with major pain relief and improved quality of life.

D’OXYVA‘s gentle vapor solution with purified medical CO2 readily dissolves in a molecular form in the skin, acting as a catalyst to improve skin perfusion pressure and optimize nerve functions and microcirculation. 


Non-electrical, handheld, painless


Fast & easy use virtually anywhere


Watch how easy it is to use D’OXYVA >>


*Six years of excellent user feedback and over two dozen clinical studies demonstrated outsized results at clinics and at home with zero adverse events. For example, significant results have also been recorded for D’OXYVA®   (deoxyhemoglobin vasodilator) as a varicose vein treatment while delivering major clinical outcomes for well over 90% of users. Average results are rounded for display, based on number of enrolled subjects in each clinical study with D’OXYVA and user feedback.
Read D’OXYVA Clinical Evidence >

**Individual results may vary. Ask your doctor before taking D’OXYVA. For prescription for medical use.
Read D’OXYVA Regulatory Statements >

***We will refund your entire D’OXYVA purchase price if you do not experience any improvements (proof of purchase required, improvements of blood flow [perfusion index] measured from absolute baseline without taking D’OXYVA).
Read Circularity’s Return Policy >