Chronic venous insufficiency is a widespread disease of great socio-economic relevance. It is characterized by accompanying venous hypertension due to valvular dysfunction or valvular insufficiency. The high pressure in the calf veins is transmitted to small venules and skin capillaries. Characteristic symptoms are skin edema, trophic skin changes, lipodermatosclerosis, and finally venous ulcers.
These in essence microcirculation phenomena have attracted the interest of the researchers in the field of basic and clinical microcirculation. Functional and morphological changes in the microvasculature,microymphatics and the venous draining systems have been described, whose conjugated action might explain the development of chornic venous insufficiency, i.e. venous ulcers. Chronic venous insuffieciency has been particularly resistant to treatments. To counteract the high venous pressure, compression therapy has been used for many years. New develpoment includes vaso-active drugs with a preferential effect on the tone of veneous vessels and microvascular permeability. It appears that some of these drugs can restore the microvasculas and diminish leukocyte/endothelium interaction as well as micromolecular leakage.
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HOW D’OXYVA CAN HELP?
D’OXYVA is the only fully noninvasive, completely painless transdermal (over-the-skin) microcirculatory solution that has been clinically tested to significantly improve microcirculation.
The improvement of microcirculation, i.e., blood flow to the smallest blood vessels, benefits one’s health, immune system and overall sense of well-being in a variety of ways.